A bald guy who looks to be part robot, Dr. Crygor would be in great company with Dr. Scienstein and Prof. E. Gadd. They're all mad scientists. This one, however, wears a yellow jumpsuit and works on an island laboratory off the coast of Diamond City.
Dr. Crygor gleefully dances around his lab, which sits just of the coast of Diamond City. He's invented some new potion which surely had an intended effect different from what it does when Crygor ingested it. Immediately, he doubles over in pain and hops to the bathroom. That's where Dr. Crygor's series of games begins. With every flush of the toilet comes a new reality-based game, whether its sawing through a sirloin steak with a knife or getting a white cat to sleep by closing its eyes at a precise moment.
Having voided his system of the noxious substance, Dr. Crygor breaths a sigh of relief - until the toilet starts spewing forth blue liquid. He tries to swim for it, but a geyser of mystery fluid shoots Dr. Crygor high into the sky. Luckily, Ana's messenger bird Don catches him and he gently descends to the gelateria, where he meets everybody else.
Dr. Crygor also competes with Orbulon in the unlockable microgame "Versus Hurdle."
In WarioWare: Twisted, the good doctor appears initially in the game's intro sequence. Wario, infuriated at losing while playing on his Game Boy Advance, smashes the game system by throwing it across the room. He then takes the broken Game Boy Advance to Dr. Crygor, who repairs it by tossing it into a converted washing machine that seems to cause all manner of scientific innovations. The system is repaired, but without buttons, and Dr. Crygor must explain that Wario must rotate the system in order to play. Mona and 9-Volt trot on over and immediately take to the unusual game play. Immediately, Wario gets dollar signs in his eyes and decided to market the game. So, ostensibly, Dr. Crygor is supposed to be the one responsible for the tilt-and-turn gameplay you're doing as you play WarioWare: Twisted!
In his own story scenes, Dr. Crygor is seen once again inventing. He manages to rig the same washing machine to affect gravity, hence his game series title, "Gravitator," which has the player tilting the Game Boy at all angles to win. Once the games are completed, the Gravitator ruptures and a powerful mechanical suit pops out. Naturally, Dr. Crygor jumps in and takes off into the sky. He soars until he comes into contact with Shuriken, Kat's bird. The super suit disassembles, but Shuriken swoops back and snatches up Crygor before he hits the ground. Safe and on the ground, Crygor meets up with his friends at Club Sugar.
Crygor gets an upgrade, of sorts, in WarioWare: Touched!, which features him testing out a new machine that converts old things into shining new ones. He tosses in an apple core, for example, twists a crank and voila! - a brand new apple. Crygor steps into the machine to fetch the fruit, but the door closes on him. The player, this time, must twist the crank using the Nintendo DS stylus, and out steps Dr. Crygor 2.0 - more metal, more machine and now complete with jetpack. Dr. Crygor's games fall into the set "Slightly Unscrewed," as all of them necessitate the same circular stylus motion the player performed in the intro.
Once the player beats Crygor's games, he or she sees the doctor blasting into space - complete with cameos from the Space Bunnies. Then, curiously, he heads back to Earth, to the Hawt House to jam with the rest of the crew.